Diseases

c. difficile-associated diarrhea

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Clostridioides difficile is a bacterium that causes an infection of the large intestine (colon). Symptoms can range from diarrhea to life-threatening damage to the colon. The bacterium is often referred to as C. difficile or C. diff.

Symptoms

  • fever
  • watery diarrhea three or more times a day for more than one day
  • symptoms usually develop within 5 to 10 days after a course of antibiotics
  • mild abdominal cramping and tenderness
  • dehydration

Causes

  • c. difficile bacteria enter the body through the mouth. they can begin reproducing in the small intestine. when they reach the large intestine (colon), they can release tissue-damaging toxins.

Risk factors

  • taking antibiotics or other medications
  • staying in a health care facility
  • having a serious illness or medical procedure

Diagnosis

  • blood tests
  • signs and symptoms
  • stool studies.

Medicines used

Frequently asked questions

What is c. difficile-associated diarrhea?

Clostridioides difficile is a bacterium that causes an infection of the large intestine (colon). Symptoms can range from diarrhea to life-threatening damage to the colon. The bacterium is often referred to as C. difficile or C. diff.

What are the symptoms of c. difficile-associated diarrhea?

fever, watery diarrhea three or more times a day for more than one day, symptoms usually develop within 5 to 10 days after a course of antibiotics, mild abdominal cramping and tenderness, dehydration

What causes c. difficile-associated diarrhea?

c. difficile bacteria enter the body through the mouth. they can begin reproducing in the small intestine. when they reach the large intestine (colon), they can release tissue-damaging toxins.

Which medicines are used for c. difficile-associated diarrhea?

vancomycin

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