Diseases
cystic fibrosis
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Cystic fibrosis is a genetic condition. It's caused by a faulty gene that affects the movement of salt and water in and out of cells. This, along with recurrent infections, can result in a build-up of thick, sticky mucus in the body's tubes and passageways – particularly the lungs and digestive system.
Symptoms
- a persistent cough that produces thick mucus (sputum)
- wheezing
- exercise intolerance
- foul-smelling, greasy stools
- poor weight gain and growth
Causes
- in cystic fibrosis, a defect (mutation) in a gene — the cystic fibrosis transmembrane conductance regulator (cftr) gene — changes a protein that regulates the movement of salt in and out of cells.
Risk factors
- genetics
Diagnosis
- ct scan
- genetic testing
Medicines used
Frequently asked questions
What is cystic fibrosis?
Cystic fibrosis is a genetic condition. It's caused by a faulty gene that affects the movement of salt and water in and out of cells. This, along with recurrent infections, can result in a build-up of thick, sticky mucus in the body's tubes and passageways – particularly the lungs and digestive system.
What are the symptoms of cystic fibrosis?
a persistent cough that produces thick mucus (sputum), wheezing, exercise intolerance, foul-smelling, greasy stools, poor weight gain and growth
What causes cystic fibrosis?
in cystic fibrosis, a defect (mutation) in a gene — the cystic fibrosis transmembrane conductance regulator (cftr) gene — changes a protein that regulates the movement of salt in and out of cells.
Which medicines are used for cystic fibrosis?
aztreonam, tobramycin
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