Diseases

cytokine release syndrome

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Cytokine release syndrome (CRS) happens when your immune system responds to infection or immunotherapy drugs more aggressively than it should. CRS symptoms include fever, nausea, fatigue and body aches. Prompt treatment is essential, as symptoms can worsen quickly.

Symptoms

  • fever
  • nausea and vomiting
  • chills
  • tiredness
  • low blood pressure

Causes

  • infection and immunotherapies are the two main triggers for cytokine release

Risk factors

  • infections

Diagnosis

  • blood tests. ie cbc
  • imaging tests (such as x-rays, ct scans or mri)

Medicines used

Frequently asked questions

What is cytokine release syndrome?

Cytokine release syndrome (CRS) happens when your immune system responds to infection or immunotherapy drugs more aggressively than it should. CRS symptoms include fever, nausea, fatigue and body aches. Prompt treatment is essential, as symptoms can worsen quickly.

What are the symptoms of cytokine release syndrome?

fever, nausea and vomiting, chills, tiredness, low blood pressure

What causes cytokine release syndrome?

infection and immunotherapies are the two main triggers for cytokine release

Which medicines are used for cytokine release syndrome?

tocilizumab

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