Diseases

liver transplant rejection

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Rejection is when your body's immune system starts to 'attack' your transplanted liver. It happens when your immune system recognises the liver as coming from a different person and thinks it isn't supposed to be there. Rejection can still occur even if you're taking all of your medicines.

Symptoms

  • fever greater than 38° c.
  • jaundice - yellowing of the skin and eyes.
  • itching.
  • dark urine.
  • abdominal swelling or tenderness.

Causes

  • the body's immune system starts to 'attack' the transplanted liver.

Risk factors

  • hla-dr mismatch
  • longer cold ischemic time
  • older donor age

Diagnosis

  • diagnosis usually requires a liver biopsy
  • signs and symptoms.

Medicines used

Frequently asked questions

What is liver transplant rejection?

Rejection is when your body's immune system starts to 'attack' your transplanted liver. It happens when your immune system recognises the liver as coming from a different person and thinks it isn't supposed to be there. Rejection can still occur even if you're taking all of your medicines.

What are the symptoms of liver transplant rejection?

fever greater than 38° c., jaundice - yellowing of the skin and eyes., itching., dark urine., abdominal swelling or tenderness.

What causes liver transplant rejection?

the body's immune system starts to 'attack' the transplanted liver.

Which medicines are used for liver transplant rejection?

basiliximab

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