Diseases
mantle cell lymphoma
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Mantle Cell lymphoma (MCL) is an aggressive, rare form of non-Hodgkin lymphoma (NHL) that arises from cells originating in the “mantle zone.” The mantle zone is the outer ring of small lymphocytes surrounding the center of a lymphatic nodule. MCL accounts for roughly six percent of all NHL cases in the United States.
Symptoms
- nausea and vomiting or diarrhea.
- swollen lymph nodes in your neck, armpits or groin.
- heartburn, belly pain or bloating.
- a sense of fullness or discomfort from enlarged tonsils, enlarged liver
- pressure or pain in your lower back, often going down one or both legs.
Causes
- most of the time, mantle cell lymphoma happens when certain genes mutate and change how your b lymphocytes function
Risk factors
- mantle cell lymphoma typically affects people between the ages of 60 and 80
Diagnosis
- complete blood count (cbc) with differential.
- lactate dehydrogenase (ldh) test.
- uric acid level test.
- bone marrow aspiration and biopsy.
Medicines used
Frequently asked questions
What is mantle cell lymphoma?
Mantle Cell lymphoma (MCL) is an aggressive, rare form of non-Hodgkin lymphoma (NHL) that arises from cells originating in the “mantle zone.” The mantle zone is the outer ring of small lymphocytes surrounding the center of a lymphatic nodule. MCL accounts for roughly six percent of all NHL cases in the United States.
What are the symptoms of mantle cell lymphoma?
nausea and vomiting or diarrhea., swollen lymph nodes in your neck, armpits or groin., heartburn, belly pain or bloating., a sense of fullness or discomfort from enlarged tonsils, enlarged liver, pressure or pain in your lower back, often going down one or both legs.
What causes mantle cell lymphoma?
most of the time, mantle cell lymphoma happens when certain genes mutate and change how your b lymphocytes function
Which medicines are used for mantle cell lymphoma?
lenalidomide
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