Diseases
microscopic polyangiitis
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Microscopic polyangiitis is an idiopathic autoimmune disease characterized by a systemic vasculitis that predominantly affects the small- caliber blood vessels, and is associated with the presence of antineutrophil cytoplasmic autoantibodies (ANCA).
Symptoms
- because many different organ systems may be involved, a wide range of symptoms
- is present, ie, feel generally ill and fatigued, have a fever
- or a loss of appetite and weight.
- shortness of breath or cough up of blood.
- abnormal sensation followed by numbness or loss of strength.
Causes
- the cause of mpa is unknown. mpa isn’t a form of cancer, isn’t contagious and doesn’t usually occur within families
Risk factors
- occupational
- environmental
- genetic, or autoimmune conditions.
Diagnosis
- blood tests
- physical examination
- urinalysis
- computed tomography (ct) or magnetic resonance (mr) scans,
Medicines used
Frequently asked questions
What is microscopic polyangiitis?
Microscopic polyangiitis is an idiopathic autoimmune disease characterized by a systemic vasculitis that predominantly affects the small- caliber blood vessels, and is associated with the presence of antineutrophil cytoplasmic autoantibodies (ANCA).
What are the symptoms of microscopic polyangiitis?
because many different organ systems may be involved, a wide range of symptoms, is present, ie, feel generally ill and fatigued, have a fever, or a loss of appetite and weight., shortness of breath or cough up of blood., abnormal sensation followed by numbness or loss of strength.
What causes microscopic polyangiitis?
the cause of mpa is unknown. mpa isn’t a form of cancer, isn’t contagious and doesn’t usually occur within families
Which medicines are used for microscopic polyangiitis?
rituximab
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