Diseases

myasthenia gravis

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Myasthenia gravis is a rare long-term condition that causes muscle weakness. It most commonly affects the muscles that control the eyes and eyelids, facial expressions, chewing, swallowing and speaking. But it can affect most parts of the body.

Symptoms

  • droopy eyelids
  • double vision
  • difficulty making facial expressions
  • problems chewing and difficulty swallowing
  • slurred speech
  • weak arms, legs or neck

Causes

  • In myasthenia gravis, the immune system produces antibodies that block or destroy many of the muscles' receptor sites for a neurotransmitter called acetylcholine
  • Rarely, mothers with myasthenia gravis have children who are born with myasthenia gravis

Risk factors

  • Thymus gland tumors
  • Underactive or overactive thyroid.

Diagnosis

  • Ice pack test
  • Blood analysis
  • Repetitive nerve stimulation
  • Single-fiber electromyography (EMG)

Medicines used

Frequently asked questions

What is myasthenia gravis?

Myasthenia gravis is a rare long-term condition that causes muscle weakness. It most commonly affects the muscles that control the eyes and eyelids, facial expressions, chewing, swallowing and speaking. But it can affect most parts of the body.

What are the symptoms of myasthenia gravis?

droopy eyelids, double vision, difficulty making facial expressions, problems chewing and difficulty swallowing, slurred speech, weak arms, legs or neck

What causes myasthenia gravis?

In myasthenia gravis, the immune system produces antibodies that block or destroy many of the muscles' receptor sites for a neurotransmitter called acetylcholine; Rarely, mothers with myasthenia gravis have children who are born with myasthenia gravis

Which medicines are used for myasthenia gravis?

neostigmine, pyridostigmine

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