Diseases
myeloproliferative diseases
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
MPDs are blood cancers caused by changes in the stem cells inside bone marrow, the tissue that makes blood cells. These changes cause the body to make too many blood cells. This excess can be any type of blood cell — white, red, or platelets.
Symptoms
- fatigue
- shortness of breath.
- weakness and malaise.
- loss of appetite.
- pale skin.
Causes
- environment. overexposure to radiation, electrical wiring, or chemicals.
- genetics. research has linked changes in the jak2 and tet2 genes to an increased risk of polycythemia vera.
Risk factors
- the risk factors (age, environmental exposure, and gender) differ for each type
- people between 45 and 50 are at higher risk of chronic myelogenous leukemia
- people older than 60 are at risk of essential thrombocytosis
Diagnosis
- blood tests
- bone marrow sample
Medicines used
Frequently asked questions
What is myeloproliferative diseases?
MPDs are blood cancers caused by changes in the stem cells inside bone marrow, the tissue that makes blood cells. These changes cause the body to make too many blood cells. This excess can be any type of blood cell — white, red, or platelets.
What are the symptoms of myeloproliferative diseases?
fatigue, shortness of breath., weakness and malaise., loss of appetite., pale skin.
What causes myeloproliferative diseases?
environment. overexposure to radiation, electrical wiring, or chemicals.; genetics. research has linked changes in the jak2 and tet2 genes to an increased risk of polycythemia vera.
Which medicines are used for myeloproliferative diseases?
imatinib
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