Diseases

myxedema coma

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Myxedema coma is defined as severe hypothyroidism leading to decreased mental status, hypothermia, and other symptoms related to slowing of function in multiple organs. It is a medical emergency with a high mortality rate.

Symptoms

  • fatigue
  • constipation
  • weight gain
  • cold intolerance
  • a deep voice

Causes

  • decompensation into myxedema coma occurs when the hypothyroid patient's homeostatic mechanisms are disrupted.

Risk factors

  • infections, particularly pneumonia and urosepsis

Diagnosis

  • physical exam.
  • results of the total serum thyroxine and free thyroxine index tests

Medicines used

Frequently asked questions

What is myxedema coma?

Myxedema coma is defined as severe hypothyroidism leading to decreased mental status, hypothermia, and other symptoms related to slowing of function in multiple organs. It is a medical emergency with a high mortality rate.

What are the symptoms of myxedema coma?

fatigue, constipation, weight gain, cold intolerance, a deep voice

What causes myxedema coma?

decompensation into myxedema coma occurs when the hypothyroid patient's homeostatic mechanisms are disrupted.

Which medicines are used for myxedema coma?

levothyroxine

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