Diseases

parathyroid carcinoma

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Parathyroid carcinoma is a rare endocrine malignancy. It accounts for <1% of cases of sporadic primary hyperparathyroidism (PHPT) and is usually associated with more severe clinical manifestations than its much more common benign counterpart, parathyroid adenoma. (1–3) Its course is typically indolent but progressive.

Symptoms

  • having to pee more often than usual (frequent urination).
  • being thirstier than usual.
  • nausea and vomiting.
  • not feeling as hungry as usual.
  • feeling really tired.

Causes

  • there isn’t a known cause of parathyroid cancer.

Risk factors

  • multiple endocrine neoplasia type i (men1).
  • familial isolated hyperparathyroidism (fihp).
  • hyperparathyroidism-jaw tumor syndrome.

Diagnosis

  • blood calcium test.
  • blood pth (parathyroid hormone) test.
  • parathyroid scan (typically a radioactive sestamibi scan and/or ct scan).
  • ct (computerized tomography) scan

Medicines used

Frequently asked questions

What is parathyroid carcinoma?

Parathyroid carcinoma is a rare endocrine malignancy. It accounts for <1% of cases of sporadic primary hyperparathyroidism (PHPT) and is usually associated with more severe clinical manifestations than its much more common benign counterpart, parathyroid adenoma. (1–3) Its course is typically indolent but progressive.

What are the symptoms of parathyroid carcinoma?

having to pee more often than usual (frequent urination)., being thirstier than usual., nausea and vomiting., not feeling as hungry as usual., feeling really tired.

What causes parathyroid carcinoma?

there isn’t a known cause of parathyroid cancer.

Which medicines are used for parathyroid carcinoma?

cinacalcet

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