Diseases
periodic paralysis
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Periodic paralysis (PP) is a rare neuromuscular disorder related to a defect in muscle ion channels, characterized by episodes of painless muscle weakness, which may be precipitated by heavy exercise, fasting, or high-carbohydrate meals.
Symptoms
- attacks of muscle weakness that may last for minutes to days.
- muscle pain in muscles after exercise.
- muscle cramping.
- feeling tingles.
- permanent weakness, more likely later in life.
Causes
- attacks may result from low blood levels of potassium. other triggers may include strenuous exercise, foods with a lot of sugars and starches (carbohydrates), licorice, stress, cold temperatures, and certain medicines.
Risk factors
- strenuous exercise
- foods with a lot of sugars and starches
Diagnosis
- physical exam.
- blood tests for potassium levels during an attack.
- genetic testing
Medicines used
Frequently asked questions
What is periodic paralysis?
Periodic paralysis (PP) is a rare neuromuscular disorder related to a defect in muscle ion channels, characterized by episodes of painless muscle weakness, which may be precipitated by heavy exercise, fasting, or high-carbohydrate meals.
What are the symptoms of periodic paralysis?
attacks of muscle weakness that may last for minutes to days., muscle pain in muscles after exercise., muscle cramping., feeling tingles., permanent weakness, more likely later in life.
What causes periodic paralysis?
attacks may result from low blood levels of potassium. other triggers may include strenuous exercise, foods with a lot of sugars and starches (carbohydrates), licorice, stress, cold temperatures, and certain medicines.
Which medicines are used for periodic paralysis?
dichlorphenamide
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