Diseases

wegener granulomatosis

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Overview

Granulomatosis with polyangiitis is an uncommon disorder that causes inflammation of the blood vessels in your nose, sinuses, throat, lungs and kidneys. Formerly called Wegener's granulomatosis, this condition is one of a group of blood vessel disorders called vasculitis. It slows blood flow to some of your organs.

Symptoms

  • fever
  • pus-like drainage with crusts from your nose, stuffiness, sinus infections
  • coughing, sometimes with bloody phlegm
  • shortness of breath or wheezing
  • numbness in your limbs, fingers or toes

Causes

  • the cause of granulomatosis with polyangiitis isn't known. it's not contagious, and there's no evidence that it's inherited.

Risk factors

  • granulomatosis with polyangiitis can occur at any age. it most often affects ...
  • ... people between the ages of 40 and 65.

Diagnosis

  • lab tests
  • biopsy
  • imaging tests

Medicines used

Frequently asked questions

What is wegener granulomatosis?

Granulomatosis with polyangiitis is an uncommon disorder that causes inflammation of the blood vessels in your nose, sinuses, throat, lungs and kidneys. Formerly called Wegener's granulomatosis, this condition is one of a group of blood vessel disorders called vasculitis. It slows blood flow to some of your organs.

What are the symptoms of wegener granulomatosis?

fever, pus-like drainage with crusts from your nose, stuffiness, sinus infections, coughing, sometimes with bloody phlegm, shortness of breath or wheezing, numbness in your limbs, fingers or toes

What causes wegener granulomatosis?

the cause of granulomatosis with polyangiitis isn't known. it's not contagious, and there's no evidence that it's inherited.

Which medicines are used for wegener granulomatosis?

rituximab

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