Drug reference

abiraterone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Adrenocortical Drugs)

Mechanism of action

Androgen biosynthesis inhibitor that inhibits 17 alpha-hydroxylase/C17, 20-lyase (CYP17); this enzyme is expressed in testicular, adrenal, and prostatic tumor tissues and is required for androgen biosynthesis

Common side effects

  • Fatigue
  • Increased AST
  • Lymphopenia
  • Hyperglycemia
  • Hypertriglyceridemia
  • Increased ALT

Known interactions (1)

Related conditions

Frequently asked questions

What drug class is abiraterone?

abiraterone belongs to: Endocrine.

How does abiraterone work?

Androgen biosynthesis inhibitor that inhibits 17 alpha-hydroxylase/C17, 20-lyase (CYP17); this enzyme is expressed in testicular, adrenal, and prostatic tumor tissues and is required for androgen biosynthesis

What are the common side effects of abiraterone?

Fatigue, Increased AST, Lymphopenia, Hyperglycemia, Hypertriglyceridemia, Increased ALT

Which drugs interact with abiraterone?

spironolactone

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