Drug reference
cetuximab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Monoclonal antibody(Oncology))
Mechanism of action
Recombinant humanized monoclonal antibody, Binds specifically to the EGF receptor (EGFR, HER1, c-ErbB-1) on both normal and tumor cells, Competitively inhibits the binding of EGF NS other ligands, such as TGF-alpha. Blocks phosphorylation and activation of receptor-associated kinases, resulting in inhibition of cell growth, induction of apoptosis.
Common side effects
- Constipation
- Fatigue
- Nausea
- Pain
- Dry skin
- Dyspnea
- Rash/desquamation
Related conditions
Frequently asked questions
What drug class is cetuximab?
cetuximab belongs to: Oncology.
How does cetuximab work?
Recombinant humanized monoclonal antibody, Binds specifically to the EGF receptor (EGFR, HER1, c-ErbB-1) on both normal and tumor cells, Competitively inhibits the binding of EGF NS other ligands, such as TGF-alpha. Blocks phosphorylation and activation of receptor-associated kinases, resulting in inhibition of cell growth, induction of apoptosis.
What are the common side effects of cetuximab?
Constipation, Fatigue, Nausea, Pain, Dry skin, Dyspnea, Rash/desquamation
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