Drug reference
Factor VIIa recombinant
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Miscellaneous(CVS))
Mechanism of action
Activates conversion of Factor X to Factor Xa, which initiates the common pathway of the coagulation cascade; prothrombin is activated to thrombin, which then converts fibrinogen to fibrin to form a hemostatic plug, thereby achieving clot formation at the site of hemorrhage (hemostasis)
Common side effects
- Dizziness
- Headache
- Fever
- Infusion-related reactions
Boxed warnings
- Serious arterial and venous thrombotic and thromboembolic events following administration reported Discuss risks and explain signs and symptoms of thromboembolic events with patients Monitor for signs or symptoms of activation of the coagulation system and for thrombosis
Contraindications
- Known allergy to rabbits, rabbit proteins, or any product components; exposure can result in severe hypersensitivity reaction
Related conditions
Frequently asked questions
What drug class is Factor VIIa recombinant?
Factor VIIa recombinant belongs to: Cardiovascular.
How does Factor VIIa recombinant work?
Activates conversion of Factor X to Factor Xa, which initiates the common pathway of the coagulation cascade; prothrombin is activated to thrombin, which then converts fibrinogen to fibrin to form a hemostatic plug, thereby achieving clot formation at the site of hemorrhage (hemostasis)
What are the common side effects of Factor VIIa recombinant?
Dizziness, Headache, Fever, Infusion-related reactions
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