Drug reference
inclisiran
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Miscellaneous(CVS))
Mechanism of action
Small interfering ribonucleic acid (siRNA) directed to proprotein convertase subtilisin kexin type 9 (PCSK9); inclisiran is conjugated on the sense strand with triantennary N-Acetylgalactosamine (GalNAc) to facilitate uptake by hepatocytes, LDL-C is cleared from the circulation preferentially through the LDL receptor (LDLR) pathway
Common side effects
- Injection site reaction
- Arthralgia
- Bronchitis
- Urinary tract infection
- Diarrhea
Related conditions
Frequently asked questions
What drug class is inclisiran?
inclisiran belongs to: Cardiovascular.
How does inclisiran work?
Small interfering ribonucleic acid (siRNA) directed to proprotein convertase subtilisin kexin type 9 (PCSK9); inclisiran is conjugated on the sense strand with triantennary N-Acetylgalactosamine (GalNAc) to facilitate uptake by hepatocytes, LDL-C is cleared from the circulation preferentially through the LDL receptor (LDLR) pathway
What are the common side effects of inclisiran?
Injection site reaction, Arthralgia, Bronchitis, Urinary tract infection, Diarrhea
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