Drug reference
lofexidine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Miscellaneous(CNS))
Mechanism of action
Centrally acting alpha2-agonist that binds to receptors on adrenergic neurons; this reduces the release of norepinephrine and decreases sympathetic tone
Common side effects
- Insomnia
- Dizziness
- Bradycardia
- Hypotension
- Orthostatic hypotension
Related conditions
Frequently asked questions
What drug class is lofexidine?
lofexidine belongs to: Central Nervous System.
How does lofexidine work?
Centrally acting alpha2-agonist that binds to receptors on adrenergic neurons; this reduces the release of norepinephrine and decreases sympathetic tone
What are the common side effects of lofexidine?
Insomnia, Dizziness, Bradycardia, Hypotension, Orthostatic hypotension
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