Drug reference
mesna
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Genitourinary (Miscellaneous(Genitourinary))
Mechanism of action
Oxidized to dimesna in the blood, and is in turn reduced back to mesna in the kidney; synthetic sulfhydryl (thiol) compound binds & detoxifies ifosfamide metabolite acrolein in bladder/kidney
Common side effects
- Asthenia
- Anorexia
- Vomiting
- Nausea
Related conditions
Frequently asked questions
What drug class is mesna?
mesna belongs to: Genitourinary.
How does mesna work?
Oxidized to dimesna in the blood, and is in turn reduced back to mesna in the kidney; synthetic sulfhydryl (thiol) compound binds & detoxifies ifosfamide metabolite acrolein in bladder/kidney
What are the common side effects of mesna?
Asthenia, Anorexia, Vomiting, Nausea
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