Drug reference

misoprostol

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Gastrointestinal Tract (Miscellaneous(GIT))

Mechanism of action

Synthetic prostaglandin E analogue parent drug that is rapidly deesterified to misoprostol acid (active metabolite) and replaces protective prostaglandins consumed with therapies that inhibit prostaglandin synthesis; inhibits gastric acid secretion and protects gastric mucosa.

Common side effects

  • Headache
  • Abdominal pain
  • Diarrhea

Contraindications

  • Pregnancy when used to reduce risk of NSAID-induced ulcers Hypersensitivity to misoprostol, prostaglandins, or prostaglandin analogues

Related conditions

Frequently asked questions

What drug class is misoprostol?

misoprostol belongs to: Gastrointestinal Tract.

How does misoprostol work?

Synthetic prostaglandin E analogue parent drug that is rapidly deesterified to misoprostol acid (active metabolite) and replaces protective prostaglandins consumed with therapies that inhibit prostaglandin synthesis; inhibits gastric acid secretion and protects gastric mucosa.

What are the common side effects of misoprostol?

Headache, Abdominal pain, Diarrhea

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