Drug reference
permethrin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Dermatology (Lice Drugs)
Mechanism of action
Like natural pyrethrins, permethrin acts as a neurotoxin by depolarizing nerve cell membranes of parasites. The drug disrupts sodium ion influx through cell membrane channels by which membrane repolarization is regulated, Delayed repolarization results in paralysis of nerves in the exoskeletal respiratory muscles of parasite leading to death.
Common side effects
- Pruritus
- Mild and transient burning and stinging
Related conditions
Frequently asked questions
What drug class is permethrin?
permethrin belongs to: Dermatology.
How does permethrin work?
Like natural pyrethrins, permethrin acts as a neurotoxin by depolarizing nerve cell membranes of parasites. The drug disrupts sodium ion influx through cell membrane channels by which membrane repolarization is regulated, Delayed repolarization results in paralysis of nerves in the exoskeletal respiratory muscles of parasite leading to death.
What are the common side effects of permethrin?
Pruritus, Mild and transient burning and stinging
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