Drug interactions
Acetazolamide + Zonisamide
Severity: Moderate
Acetazolamide and Zonisamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs inhibit carbonic anhydrase, so combined use may amplify metabolic acidosis and raise the risk of kidney stones (nephrolithiasis) and paresthesias.
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Other interactions of Acetazolamide
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