Drug reference

zonisamide

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Central Nervous System (Anti Epileptic Drugs)

Mechanism of action

Unknown; benzisoxazole compound; more active against tonic phase than it is against clonic phase; may stabilize neuronal membranes by acting at sodium and calcium channels; does not affect GABA activity

Common side effects

  • Agitation
  • Anorexia
  • Dizziness
  • Somnolence
  • Headache
  • Fatigue
  • Nausea

Related conditions

Frequently asked questions

What drug class is zonisamide?

zonisamide belongs to: Central Nervous System.

How does zonisamide work?

Unknown; benzisoxazole compound; more active against tonic phase than it is against clonic phase; may stabilize neuronal membranes by acting at sodium and calcium channels; does not affect GABA activity

What are the common side effects of zonisamide?

Agitation, Anorexia, Dizziness, Somnolence, Headache, Fatigue, Nausea

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference