Drug interactions
Acetylsalicylic acid + Duloxetine
Severity: Moderate
Acetylsalicylic acid and Duloxetine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Duloxetine, like other serotonergic antidepressants, increases bleeding risk, especially upper GI bleeding, when combined with aspirin.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Acetylsalicylic acid and Duloxetine interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Free 14-day trial. No card needed.
Other interactions of Acetylsalicylic acid
Other interactions of Duloxetine
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
