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Drug interactions

Adalimumab + Rilonacept

Severity: Major

Adalimumab and Rilonacept: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Rilonacept (IL-1 blocker) combined with adalimumab (TNF blocker) raises the risk of serious infection, as with other combinations of biologic cytokine inhibitors, without proven added benefit.

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