Drug reference
adalimumab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (TNF-alpha Inhibitors)
Mechanism of action
Recombinant human anti-TNF-α IgG1 monoclonal antibody; blocks inflammatory activity of TNF-α; specifically binds to TNF-α and blocks its interaction with p55 and p75 cell surface TNF receptors; also lyses surface TNF-expressing cells in vitro and modulates biologic responses responsible for leukocyte migration.
Common side effects
- Upper respiratory tract infection
- Injection site pain
- Rash
- Sinusitis
- Increased creatine phosphokinase
Known interactions (5)
- adalimumab + measles mumps and rubella vaccine Contraindicated
- abatacept + adalimumab Major
- adalimumab + upadacitinib Major
- adalimumab + hepatitis a vaccine inactivated Moderate
- adalimumab + pneumococcal vaccine 13-valent Moderate
Related conditions
Frequently asked questions
What drug class is adalimumab?
adalimumab belongs to: Musculoskeletal.
How does adalimumab work?
Recombinant human anti-TNF-α IgG1 monoclonal antibody; blocks inflammatory activity of TNF-α; specifically binds to TNF-α and blocks its interaction with p55 and p75 cell surface TNF receptors; also lyses surface TNF-expressing cells in vitro and modulates biologic responses responsible for leukocyte migration.
What are the common side effects of adalimumab?
Upper respiratory tract infection, Injection site pain, Rash, Sinusitis, Increased creatine phosphokinase
Which drugs interact with adalimumab?
measles mumps and rubella vaccine, abatacept, upadacitinib, hepatitis a vaccine inactivated, pneumococcal vaccine 13-valent
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