Drug interactions
Ado-trastuzumab + Istradefylline
Severity: Minor
Ado-trastuzumab and Istradefylline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
At 40 mg/day istradefylline weakly inhibits CYP3A4 and may raise DM1 exposure from ado-trastuzumab emtansine.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Ado-trastuzumab and Istradefylline interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Ado-trastuzumab
Drug class
- Ado-trastuzumab
- Oncology
- Istradefylline
- Central Nervous System
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
