Drug interactions
Ado-trastuzumab emtansine + Apalutamide
Severity: Moderate
Ado-trastuzumab emtansine and Apalutamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The DM1 cytotoxic component of ado-trastuzumab emtansine is metabolized by CYP3A4, and apalutamide is a strong CYP3A4 inducer.
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Other interactions of Apalutamide
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