Drug interactions
Ado-trastuzumab emtansine + Ketoconazole
Severity: Major
Ado-trastuzumab emtansine and Ketoconazole: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The DM1 cytotoxic payload is metabolized by CYP3A4, so ketoconazole may raise DM1 exposure.
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Other interactions of Ketoconazole
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