Drug interactions
Ado-trastuzumab emtansine + Ribociclib
Severity: Moderate
Ado-trastuzumab emtansine and Ribociclib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The DM1 payload of ado-trastuzumab emtansine is metabolized by CYP3A4, so ribociclib may increase DM1 exposure.
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Other interactions of Ribociclib
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