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Drug interactions

Allopurinol + Sodium bicarbonate

Severity: Minor

Allopurinol and Sodium bicarbonate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oral sodium bicarbonate raises gastric pH and may reduce the absorption of allopurinol, potentially lowering its urate-lowering effect.

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