Drug reference
allopurinol
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Genitourinary (Anti Gout)
Mechanism of action
Xanthine oxidase inhibitor; inhibits conversion of hypoxanthine to xanthine to uric acid; decreases production of uric acid without disrupting synthesis of vital purines.
Common side effects
- Rash
- Vomiting
- Nausea
- Renal failure
Contraindications
- Patients with a history of severe reaction to any formulation of this drug
Known interactions (4)
Related conditions
Frequently asked questions
What drug class is allopurinol?
allopurinol belongs to: Genitourinary.
How does allopurinol work?
Xanthine oxidase inhibitor; inhibits conversion of hypoxanthine to xanthine to uric acid; decreases production of uric acid without disrupting synthesis of vital purines.
What are the common side effects of allopurinol?
Rash, Vomiting, Nausea, Renal failure
Which drugs interact with allopurinol?
azathioprine, didanosine, amoxicillin/clavulanate, amoxicillin/clavulanate (Augmentin)
Full monographs, dosing and an interaction checker in the MediHelp app
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