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Drug interactions

Allopurinol + Theophylline

Severity: Moderate

Allopurinol and Theophylline: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

High-dose allopurinol can reduce theophylline clearance and raise serum levels, risking nausea, tachycardia, arrhythmias and seizures.

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