Drug interactions
Allopurinol + Thioguanine
Severity: Minor
Allopurinol and Thioguanine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Unlike mercaptopurine, thioguanine is metabolized by thiopurine methyltransferase and deaminase rather than xanthine oxidase, so allopurinol does not require major thioguanine dose reduction.
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Other interactions of Allopurinol
Other interactions of Thioguanine
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