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Drug interactions

Alogliptin-pioglitazone + Phenytoin

Severity: Moderate

Alogliptin-pioglitazone and Phenytoin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Phenytoin induces CYP enzymes involved in pioglitazone metabolism, which may reduce pioglitazone exposure and glucose-lowering effect.

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Drug class

Alogliptin-pioglitazone
Endocrine
Phenytoin
Central Nervous System

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