Drug interactions
Alteplase + Reteplase
Severity: Contraindicated
Alteplase and Reteplase: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Giving two thrombolytics together duplicates therapy and substantially raises the risk of major bleeding, including intracranial hemorrhage.
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Other interactions of Alteplase
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