Drug interactions
Alvimopan + Codeine
Severity: Contraindicated
Alvimopan and Codeine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alvimopan antagonises peripheral mu-opioid receptors, and patients who have taken opioids for more than 7 days can have exaggerated gastrointestinal effects including pain, nausea, vomiting and diarrhea.
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Other interactions of Codeine
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