Drug interactions
Alvimopan + Methadone
Severity: Contraindicated
Alvimopan and Methadone: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alvimopan is a peripherally acting mu-opioid antagonist, and patients who have taken opioids such as methadone for more than a week are more sensitive to its effects.
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Other interactions of Methadone
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