Drug interactions
Alvimopan + Verapamil
Severity: Minor
Alvimopan and Verapamil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Verapamil inhibits P-glycoprotein and could slightly raise alvimopan exposure. Alvimopan is used short term in hospitalized patients, and no significant clinical effect has been established.
What this interaction means in plain words
Alvimopan and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
P-glycoprotein inhibition by verapamil may reduce alvimopan efflux.
What to do
No routine adjustment is needed; observe for gastrointestinal or cardiovascular adverse effects during the short course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Verapamil
- Acebutolol + Verapamil Major
Frequently asked questions
Can I take Alvimopan with Verapamil?
MediHelp rates the interaction as minor. Alvimopan and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Verapamil inhibits P-glycoprotein and could slightly raise alvimopan exposure. Alvimopan is used short term in hospitalized patients, and no significant clinical effect has been established.
How serious is the interaction between Alvimopan and Verapamil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; observe for gastrointestinal or cardiovascular adverse effects during the short course.
What other medicines interact with Verapamil?
MediHelp also lists interactions of Verapamil with, for example, Acebutolol. The full list is on the Verapamil page.
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