Drug interactions
Amantadine + Memantine
Severity: Moderate
Amantadine and Memantine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are NMDA receptor antagonists, so combining them can increase CNS adverse effects such as agitation, dizziness, confusion, hallucinations and insomnia.
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Other interactions of Amantadine
Other interactions of Memantine
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