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Drug interactions

Amikacin + Bumetanide

Severity: Major

Amikacin and Bumetanide: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Loop diuretics given with amikacin increase the risk of hearing and vestibular damage, which may be permanent, and volume depletion can worsen aminoglycoside nephrotoxicity.

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