Drug reference
bumetanide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Diuretics)
Mechanism of action
Inhibits reabsorption of sodium and chloride in ascending loop of Henle, thereby causing excretion of water and sodium, chloride, calcium, magnesium, potassium, and hydrogen ions
Common side effects
- Hyperuricemia
- Hypokalemia
- Hyperglycemia
- Hypochloremia
- Hyponatremia
- Azotemia
- Increased serum creatinine
Boxed warnings
- Agent is potent diuretic that, if given in excessive amounts, may lead to profound diuresis with water and electrolyte depletion Careful medical supervision is required; dosing must be adjusted to patient's needs
Contraindications
- Documented hypersensitivity to bumetanide or sulfonamides Severe uncorrected electrolyte depletion, anuria, hepatic coma
Known interactions (4)
- Amlodipine/Atenolol + bumetanide Moderate
- bumetanide + Losartan Moderate
- bumetanide + Nitroglycerin Moderate
- bumetanide + Ofloxacin Moderate
Related conditions
Frequently asked questions
What drug class is bumetanide?
bumetanide belongs to: Cardiovascular.
How does bumetanide work?
Inhibits reabsorption of sodium and chloride in ascending loop of Henle, thereby causing excretion of water and sodium, chloride, calcium, magnesium, potassium, and hydrogen ions
What are the common side effects of bumetanide?
Hyperuricemia, Hypokalemia, Hyperglycemia, Hypochloremia, Hyponatremia, Azotemia, Increased serum creatinine
Which drugs interact with bumetanide?
Amlodipine/Atenolol, Losartan, Nitroglycerin, Ofloxacin
Full monographs, dosing and an interaction checker in the MediHelp app
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