Drug reference
amikacin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Aminoglycosides)
Mechanism of action
Irreversibly binds to 30S subunit of bacterial ribosomes; blocks recognition step in protein synthesis; causes growth inhibition. For gram-negative bacterial coverage of infections resistant to gentamicin and tobramycin
Common side effects
- Headache
- Nausea
- Neurotoxicity
- Hypotension
- Nephrotoxicity
- Ototoxicity
Known interactions (4)
- amikacin + cidofovir Contraindicated
- amikacin + amphotericin b Major
- amikacin + neomycin Major
- amikacin + ceftazidime Moderate
Related conditions
Frequently asked questions
What drug class is amikacin?
amikacin belongs to: Anti Bacterial.
How does amikacin work?
Irreversibly binds to 30S subunit of bacterial ribosomes; blocks recognition step in protein synthesis; causes growth inhibition. For gram-negative bacterial coverage of infections resistant to gentamicin and tobramycin
What are the common side effects of amikacin?
Headache, Nausea, Neurotoxicity, Hypotension, Nephrotoxicity, Ototoxicity
Which drugs interact with amikacin?
cidofovir, amphotericin b, neomycin, ceftazidime
Full monographs, dosing and an interaction checker in the MediHelp app
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