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Drug interactions

Amikacin + Gentamicin

Severity: Major

Amikacin and Gentamicin: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Combining two systemic aminoglycosides gives no therapeutic advantage and substantially increases the risk of nephrotoxicity, ototoxicity and neuromuscular blockade.

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