Drug reference
gentamicin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Aminoglycosides)
Mechanism of action
Aminoglycoside antibiotic for coverage of gram-negative bacteria, including Pseudomonas species; synergistic with beta lactamase against enterococci; interferes with bacterial protein synthesis by binding to 30S and 50S ribosomal subunits
Common side effects
- Allergic contact dermatitis
- Neurotoxicity (vertigo, ataxia)
- Erythema
- Gait instability
- Ototoxicity
- Transient irritation, burning, stinging
Contraindications
- Prior aminoglycoside toxicity or hypersensitivity
Known interactions (5)
- Digoxin + gentamicin Major
- furosemide + gentamicin Major
- gentamicin + vancomycin Major
- amoxicillin/clavulanate + gentamicin Moderate
- diclofenac + gentamicin Moderate
Related conditions
Frequently asked questions
What drug class is gentamicin?
gentamicin belongs to: Anti Bacterial.
How does gentamicin work?
Aminoglycoside antibiotic for coverage of gram-negative bacteria, including Pseudomonas species; synergistic with beta lactamase against enterococci; interferes with bacterial protein synthesis by binding to 30S and 50S ribosomal subunits
What are the common side effects of gentamicin?
Allergic contact dermatitis, Neurotoxicity (vertigo, ataxia), Erythema, Gait instability, Ototoxicity, Transient irritation, burning, stinging
Which drugs interact with gentamicin?
Digoxin, furosemide, vancomycin, amoxicillin/clavulanate, diclofenac
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