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Drug interactions

Amiloride + Hydrochlorothiazide-irbesartan

Severity: Major

Amiloride and Hydrochlorothiazide-irbesartan: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Amiloride and irbesartan both promote potassium retention, which can cause hyperkalemia, especially in renal impairment or diabetes.

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