Drug reference
hydrochlorothiazide-irbesartan
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Combination(CVS))
Mechanism of action
Irbesartan: Blocks binding of angiotensin II to type 1 angiotensin II receptors, causing a lowering in blood pressure; blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II. HCT: inhibits sodium reabsorption in distal renal tubules, resulting in increased excretion of water and of sodium, potassium, and hydrogen ions
Common side effects
- Hyperkalemia
- Chest pain
- Flu-like syndrome
- Musculoskeletal pain
- Abnormal urination
- Tachycardia
Known interactions (1)
Related conditions
Frequently asked questions
What drug class is hydrochlorothiazide-irbesartan?
hydrochlorothiazide-irbesartan belongs to: Cardiovascular.
How does hydrochlorothiazide-irbesartan work?
Irbesartan: Blocks binding of angiotensin II to type 1 angiotensin II receptors, causing a lowering in blood pressure; blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II. HCT: inhibits sodium reabsorption in distal renal tubules, resulting in increased excretion of water and of sodium, potassium, and hydrogen ions
What are the common side effects of hydrochlorothiazide-irbesartan?
Hyperkalemia, Chest pain, Flu-like syndrome, Musculoskeletal pain, Abnormal urination, Tachycardia
Which drugs interact with hydrochlorothiazide-irbesartan?
isocarboxazid
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