Drug interactions
Amiloride + Levosalbutamol
Severity: Minor
Amiloride and Levosalbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levosalbutamol can lower serum potassium through cellular uptake, while amiloride conserves potassium. The effects counteract each other and significant harm is unlikely, although potassium may fluctuate in renal impairment.
What this interaction means in plain words
Amiloride and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiloride belongs to Cardiovascular; Levosalbutamol belongs to Respiratory.
Why it happens
Beta2-agonist-driven potassium shift into cells opposes amiloride's inhibition of renal potassium excretion.
What to do
No routine adjustment is needed. Check serum potassium in renal impairment or with high-dose levosalbutamol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levosalbutamol
Other interactions of Amiloride
- Amiloride + Eplerenone Contraindicated
- Amiloride + Spironolactone Contraindicated
- Amiloride + Triamterene Contraindicated
- Aceclofenac + Amiloride Major
- Acemetacin + Amiloride Major
- Amiloride + Amlodipine-benazepril Major
Frequently asked questions
Can I take Amiloride with Levosalbutamol?
MediHelp rates the interaction as minor. Amiloride and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levosalbutamol can lower serum potassium through cellular uptake, while amiloride conserves potassium. The effects counteract each other and significant harm is unlikely, although potassium may fluctuate in renal impairment.
How serious is the interaction between Amiloride and Levosalbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Check serum potassium in renal impairment or with high-dose levosalbutamol.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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