Drug interactions
Amiloride + Terbutaline
Severity: Minor
Amiloride and Terbutaline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Terbutaline can lower serum potassium through cellular uptake while amiloride retains potassium. The effects oppose each other and are rarely harmful, though potassium can fluctuate in renal impairment.
What this interaction means in plain words
Amiloride and Terbutaline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amiloride belongs to Cardiovascular; Terbutaline belongs to Respiratory.
Why it happens
Beta2-agonist potassium shift into cells opposes amiloride's inhibition of renal potassium excretion.
What to do
No routine adjustment is needed. Check potassium in renal impairment or with high-dose or parenteral terbutaline.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terbutaline
Other interactions of Amiloride
- Amiloride + Eplerenone Contraindicated
- Amiloride + Spironolactone Contraindicated
- Amiloride + Triamterene Contraindicated
- Aceclofenac + Amiloride Major
- Acemetacin + Amiloride Major
- Amiloride + Amlodipine-benazepril Major
Frequently asked questions
Can I take Amiloride with Terbutaline?
MediHelp rates the interaction as minor. Amiloride and Terbutaline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Terbutaline can lower serum potassium through cellular uptake while amiloride retains potassium. The effects oppose each other and are rarely harmful, though potassium can fluctuate in renal impairment.
How serious is the interaction between Amiloride and Terbutaline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Check potassium in renal impairment or with high-dose or parenteral terbutaline.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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