Drug interactions
Aminohippurate + Atenolol-chlorthalidone
Severity: Minor
Aminohippurate and Atenolol-chlorthalidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlorthalidone and aminohippurate are both organic anions secreted by renal proximal tubule transporters. Competition could slightly reduce aminohippurate clearance and affect its use in renal plasma flow measurement.
What this interaction means in plain words
Aminohippurate and Atenolol-chlorthalidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for organic anion transporter-mediated tubular secretion.
What to do
No action is needed for routine care. If aminohippurate is used to measure renal plasma flow, take into account that chlorthalidone may slightly alter the result.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atenolol-chlorthalidone
Frequently asked questions
Can I take Aminohippurate with Atenolol-chlorthalidone?
MediHelp rates the interaction as minor. Aminohippurate and Atenolol-chlorthalidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chlorthalidone and aminohippurate are both organic anions secreted by renal proximal tubule transporters. Competition could slightly reduce aminohippurate clearance and affect its use in renal plasma flow measurement.
How serious is the interaction between Aminohippurate and Atenolol-chlorthalidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for routine care. If aminohippurate is used to measure renal plasma flow, take into account that chlorthalidone may slightly alter the result.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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