Drug interactions
Amlodipine-olmesartan + Artemether / lumefantrine
Severity: Minor
Amlodipine-olmesartan and Artemether / lumefantrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Artemether is a weak CYP3A4 inducer, and amlodipine levels might be slightly reduced during the short antimalarial course. Clinically meaningful loss of blood pressure control is unlikely.
What this interaction means in plain words
Amlodipine-olmesartan and Artemether / lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak CYP3A4 induction may increase amlodipine metabolism.
What to do
No routine change is needed; check blood pressure if the patient is symptomatic or the course is repeated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Frequently asked questions
Can I take Amlodipine-olmesartan with Artemether / lumefantrine?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Artemether / lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Artemether is a weak CYP3A4 inducer, and amlodipine levels might be slightly reduced during the short antimalarial course. Clinically meaningful loss of blood pressure control is unlikely.
How serious is the interaction between Amlodipine-olmesartan and Artemether / lumefantrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; check blood pressure if the patient is symptomatic or the course is repeated.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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